A curse solemnly pronounced by ecclesiastical authority, and accompanied by excommunication. The person or thing accursed; a curse generally; a religious offering.
- Nuttall's Standard dictionary of the English language. By Nuttall, P.Austin. Published 1914. (noun) (n.) (noun)
The solemn curse of the Church in excommunication; any curse; the thing or person so cursed.
- The Winston Simplified Dictionary. By William Dodge Lewis, Edgar Arthur Singer. Published 1919. (noun) (n.) (noun)
A curse; a separation for destruction.
- Etymological and pronouncing dictionary of the English language. By Stormonth, James, Phelp, P. H. Published 1874. (noun) (n.) (noun)
( orig.) An offering made and set up in a temple: an ecclesiastical curse: any person or thing anathematized.
- The american dictionary of the english language. By Daniel Lyons. Published 1899. (noun) (n.) (noun)
An ecclesiastical curse; imprecation.
- The Clarendon dictionary. By William Hand Browne, Samuel Stehman Haldeman. Published 1894. (noun) (n.) (noun)

Usage examples:

And, trust me, this is the rarest fishing, and the peacefulest; only see that thou fish not with the wet fly, for that is Anathema
- Angling Sketches by Andrew Lang
The eyes of gazing millions were turned upon them- the burning wrath of the king was flashing before them- the anathema of the ministers was pronounced against them.
- Sages and Heroes of the American Revolution by L. Carroll Judson
When he stood upright- which he only did if he had some really impressive anathema to launch against the Germans- he was not more than five feet eight.
- Servants of the Guns by Jeffery E. Jeffery