The act of throwing down or lying flat; the act of falling down or bowing in adoration; great depression; great loss of strength under disease.
- Nuttall's Standard dictionary of the English language. By Nuttall, P.Austin. Published 1914. (noun) (n.) (noun)
The act of throwing down or state of being thrown down; a falling down in worship; great depression; as, prostration of mind; exhaustion of the vital powers under disease; as, nervous prostration.
- The Winston Simplified Dictionary. By William Dodge Lewis, Edgar Arthur Singer. Published 1919. (noun) (n.) (noun)
The act of throwing down or laying flat; great depression or dejection; exhaustion; great dimination of the vital energies.
- Etymological and pronouncing dictionary of the English language. By Stormonth, James, Phelp, P. H. Published 1874. (noun) (n.) (noun)
Act of throwing down or laying flat: act of falling down in adoration: dejection: complete loss of strength.
- The american dictionary of the english language. By Daniel Lyons. Published 1899. (noun) (n.) (noun)
Act of prostrating; complete loss of strength or courage.
- The Clarendon dictionary. By William Hand Browne, Samuel Stehman Haldeman. Published 1894. (noun) (n.) (noun)

Usage examples:

No sooner had her head touched it, than she sank into that deep sleep of prostration which is more like a swoon than a slumber.
- Cruel As The Grave by Mrs. Emma D. E. N. Southworth
Quick prostration follows all effort, excepting when she is fired by excitement.
- Our Nervous Friends Illustrating the Mastery of Nervousness by Robert S. Carroll
The man whose one idea is of making himself and his family materially comfortable, or even rich, may not be coming to nervous prostration but he is courting a moral prostration that will deny him all the real riches of life and that will in the end reward him with a troubled mind, a great, unsatisfied longing, unless, to be sure, he is too smug and satisfied to long for anything.
- The Untroubled Mind by Herbert J. Hall